Intermediate LIST

No.

Intermediate Name

CAS No.

StructureUsage
1

7-Methoxy-4-oxo-3,4-dihydroquinazolin-6-yl acetate

179688-53-0

Constructing core structure of EGFR inhibitors.   

2

Methyl-d3-amine hydrochloride

7436-22-8

 Deuterated building block.
3

tert-Butyl (4R-cis)-6-Chloromethyl-2,2-dimethyl-1,3-dioxane-4-acetate

154026-94-5

Starting material of Rosuvastatin Calcium

4

tert-Butyl (4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetate

154026-95-6
5

(R)-(+)-1-Boc-3-aminopyrrolidine

147081-49-0

 Chiro building Block.

For Ceftobiprole, Sunvozertinib, etc.

6

tert-butyl 4-(6-aminopyridin-3-yl)piperidine-1-carboxylate

1198408-35-3

Building Block.

7Vortioxetine

508233-74-7

Intermediate of Vortioxetine

8

Vortioxetine Hydrochloric

960203-28-5
9

Di-tert-butyl Chloromethyl Phosphate

229625-50-7

Intermediate of Fosnetupitant

10

N-tert-butyl-6-chloro-4-(o-tolyl)nicotinamide

342417-04-3

Intermediate of Netupitant and Fosnetupitant

11

Methyl-[6-(4-methyl-piperazin-1-yl)-4-o-tolyl-pyridin-3-yl]-amine

290297-25-5
12

(S)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionic acid

24435-45-8

Building Block

13(R)- 3,3,3-Trifluoro-2-hydroxy-2-methylpropionic acid44864-47-3
14

(4-(2-(dimethylamino)ethoxy)phenyl)(4-hydroxyphenyl)methanone

173163-13-8

Building Block

15(S)-2-(diphenylmethyl)pyrrolidine119237-64-8

Chiral catalyst

16

(R)-2-(diphenylmethyl)pyrrolidine

22348-31-8


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